Top 10 most profitable items to sell on Amazon: is one of the best places for entrepreneurs & side hustlers to make money. With more than 300 million active users and billions in sales each year, Amazon is full of opportunities if you know what to sell. Amazon can provide a lot of wealth, however, not all best selling items are meaningfully profitable. Some categories have really tight margins while others are incredibly profitable.
In this article, we will walk you through the top 10 most profitable items to sell on Amazon based on market trends, consumer behavior, and seller statistics.
Top 10 Most Profitable Items to Sell on Amazon: Step-by-Step Guide
Here is the Amazon market-based top 10 most profitable items to sell on Amazon explained.
1. Home Fitness Equipment
With the home workout trend gaining popularity post pandemic, fitness equipment available to consumers is definitely a profitable niche. Items such as resistance bands, yoga mats, light weights and even portable treadmills fall under this category. These items always have a great mark up value, especially if they can be branded or sold as sets.
Why it’s profitable:
- Strong profitability all year around
- High perceived value
- Low manufacturing expense in bulk
Pro tip: To stay unique, consider selling more specific products like weighted hula hoops or balance trainers.
2. Private Label Supplements
With its unparalleled distribution, the supplement industry is valued in the billions and includes a catalog of products from vitamins to protein powders, and even wellness gummies. A myriad of sellers utilize private label suppliers to manufacture branded health products.
Why it’s profitable:
- Low product cost
- Subscription potential
- Loyal repeat customers
Caution: Make sure you comply with FDA and Amazon’s health product guidelines.
3. Phone Accessories
Everyone is spending money on new phone cases, screen protectors, wireless chargers, and pop sockets. Your profit margins can increase significantly if you offer bundles or trendy designs.
What makes this profitable:
- Low sourcing cost
- Lightweight and simple shipping
- High demand with every smartphone release
Pro tip: Get a head start by making accessories for phone models that haven’t been released yet.
4. Smart Home Devices
Smart plugs, light bulbs, doorbells, and security cameras are all the rage right now. Demand keeps growing because implementing smart technology into homes becomes more affordable and mainstream.
What makes this profitable:
- Tech products have strong perceived value
- Perceived value of bundled products
- Trust in reviews from Amazon shoppers — build up trust early!
Challenge: Start up costs are higher than some other items but offer greater returns long term.
5. Eco-Friendly Products
Sustainability is a strong buying motivator in 2025. Eco friendly cleaning tablets, reusable kitchen towels, and bamboo toothbrushes are on the rise.
What makes this profitable:
- Growing concern of the environment
- Unique selling proposition (USP)
- Less competition than generic household items
Bonus: Many consumers are prepared to pay more for environmentally friendly options.
6. Pet Supplies
More Americans than ever before are spending money on their pets, and Amazon is where they go for toys, treats, and grooming supplies. Think interactive toys, grooming kits, cat towers, and even pet apparel.
Why it’s profitable:
- High emotional connection = high spending
- Strong repeat customer base
- High margins on private label options
What works best: Unique or problem-solving products like automatic feeders or anxiety-reducing pet beds.
7. DIY & Craft Kits
With more people spending time at home, crafting is back in a big way. Items such as paint-by-number kits, needlework sets, candle-making kits, and even kid-friendly slime kits are in high demand.
Why it’s profitable:
- Excellent for bundling and branding
- Appealing to hobbyists and parents
- Low cost to produce with room for creative markup
Best strategy: Offer kits with all-in-one supplies and beginner guides.
8. Luxury Beauty Products
Beauty is a saturated space, but luxury or niche items such as serums, facial rollers, LED therapy masks, and organic skincare lines continue to thrive. Amazon’s “Luxury Beauty” program adds legitimacy to qualifying brands.
Why it’s profitable:
- High price point = higher profit margins
- Small, light, and easy to ship
- Massive customer base looking for skincare solutions
Important: Focus on branding and aesthetics — packaging matters just as much as product quality here.
9. Kitchen Gadgets and Tools
People love upgrading their kitchen experience. Items like manual coffee grinders, air fryer accessories, vegetable choppers, or unique silicone baking molds are frequently bought.
Why it’s profitable:
- Trending cooking content on social media drives demand
- High bundling potential
- Useful, giftable, and easy to demonstrate in videos or product pages
Make it better: Offer multi-piece kits or recipe eBooks as digital bonuses.
10. Niche Apparel and Accessories
Generic fashion is tough to break into, but niche clothing like funny graphic tees, maternity wear, compression socks, or cosplay accessories can perform extremely well.
Why it’s profitable:
- Personalization = higher value
- Print-on-demand makes entry low-risk
- People often impulse-buy unique or relatable items
What sells: Apparel aimed at a specific interest group (dog moms, gamers, nurses, etc) tends to go viral.
Bonus Tips for Success on Amazon
Top 10 most profitable items to sell on Amazon: It’s only half the job to find a profitable product. Take these actions to improve your chances of success:
- Optimize Your Listings: Add relevant keywords, and high-quality images, and write attention-grabbing bullet points.
- Get Reviews Early: Social proof is extremely important. Use Amazon’s Vine program or product inserts to ask for reviews.
- Tracking Competitor Bait: Snowball pricing shouldn’t be your only goal, find ways to add greater value.
- Use FBA (Fulfilled by Amazon): Improves speed and customer trust while boosting conversions.
- Stay On Top of Trends: Set alerts or goals with Jungle Scout, Helium 10 and Google Trends.
Final Thoughts
Top 10 most profitable items to sell on Amazon, as a platform to start or scale an eCommerce business, Amazon is the number one choice, however, depends on the smart selection of products. The ones with the most profits are not necessarily the so-called best sellers, but the ones that have strong demand, good profit margins, and limited competition.
Sellers who are new with no prior experience or those willing to expand their sell list on Amazon should consider these suggestions for niche-focused products.
With the correct tactics, even one product can turn into a six-figure business.
Hello, I am an E-commerce Expert with extensive experience providing services to numerous e-commerce brands and individuals since 2017. My primary areas of expertise include the Amazon, Walmart, and Shopify marketplaces. Linkedin
